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Recent News

Erratum to “Altered bile acid profile associates with cognitive impairment in Alzheimer’s disease—An emerging role for gut microbiome” [Alzheimer’s & Dementia 2019;15:76-92.]

In the article “Altered bile acid profile associates with cognitive impairment in Alzheimer’s disease—An emerging role for gut microbiome,” published in the January 2019 issue of Alzheimer’s & Dementia, the e-mail address listed for author Rima Kaddurah-Daouk is incorrect. The correct addresses are [email protected] and [email protected] Read More

Impact of Helicobacter pylori and/or Helicobacter pylori–related metabolic syndrome on incidence of all-cause and Alzheimer's dementia

Beydoun et al. [1], investigated in a large national retrospective cohort study the association of Helicobacter pylori (Hp) seropositivity with an incidence of all-cause and Alzheimer's disease (AD) dementia and with AD dementia mortality. Data were extracted from the National Health and Nutrition Surveys III, phase 1 (1988–1991), and 1999–2000 and were linked with Medicare and… Read More

Primary age-related tauopathy (PART) and Alzheimer's disease (AD)

Bell et al. [1] recently compared neuropathologic, genetic, and cognitive profiles in 40 primary age-related tauopathy (PART) and 130 Alzheimer's disease (AD) cases aged ≥85 years. PART, representing 22% of this consecutive oldest-old autopsy series, differed from classical AD by significantly slower rates of cognitive impairment, lower frequency of apolipoprotein E (APOE) ε4 (4.1% vs. 17.6%) but overrepresented… Read More

Detecting both current and prior Helicobacter pylori infection is important to assess its impact on dementia

We read with great interest the article written by Fani et al. on the association between Alzheimer's disease and Helicobacter pylori infection studied on a population-based cohort (Rotterdam study) [1]. The authors did not find any association between the two diseases, that is, H. pylori infection was not associated with an increased dementia incidence after a… Read More

Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia

Recent research with neuropathologic or biomarker evidence of Alzheimer's disease (AD) casts doubt on traumatic brain injury (TBI) as a risk factor for AD. We leveraged the National Alzheimer's Coordinating Center to examine the association between self-reported TBI with loss of consciousness and AD neuropathologic changes, and with baseline and longitudinal clinical status. Read More
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